Discovering genomics, proteomics, and bioinformatics/ by A. Malcolm Campbell

Index included

Genome Sequences -- Genome Sequence Acquisition and Analysis -- Defining Genomes -- What Is Genomics? -- How Are Whole Genomes Sequenced? -- What Is an E-Value? -- Why Do the Databases Contain So Many Partial Sequences? -- How Do We Make Sense of All These Bases? -- Which Draft Sequence Is Better? -- Can We Predict Protein Functions? -- How Well Are Genes Conserved in Diverse Species? -- How Do You Know Which Bases Form a Gene? -- How Many Proteins Can One Gene Make? -- What Have We Learned from the Human Genome Draft Sequences? -- Overview of Human Genome First Draft -- Summary Statements -- Whose DNA Did We Sequence? -- How Do You Fit a Line to Data? -- Can We Describe a Typical Human Gene? -- When Are the Data Sufficient? -- Can the Genome Alter Gene Expression Without Changing the DNA Sequence? -- Genome Sequences Answer Interesting Questions -- Evolution of Genomes -- How Did Eukaryotes Evolve? -- Are the Hit Numbers Significantly Different? -- What Is the Origin of Our Species? -- How Do You Know if the Tree Is Right? -- Genomic Identifications -- How Can We Identify Biological Weapons? -- How Long Can DNA Survive? -- How Did Tuberculosis Reach North America? -- How Are Newly Emerging Diseases Identified? -- Biomedical Genome Research -- Can We Use Genomic Sequences to Make New Vaccines? -- Can We Make New Types of Antibiotics? -- Can We Invent New Types of Medication? -- How Can E. coli Be Lethal and in Our Intestines at the Same Time? -- How Can You Tell if Base Compositions Are Different? -- Genomic Variations.

A first textbook for upper-level undergraduates and first-year graduate students which combines integrated Web exercises with a problem-solving approach to train students in basic hands-on genomic